Perceptions is publishing its second issue with its new design. The editorial team and board have worked hard on improving the style and quality of the journal. Perceptions has a new deputy editor, Dr. Mesut Özcan, who recently joined the Center for Strategic Research (SAM). The SAM staff continues their hard work in restructuring the center so that it can establish itself as an influential and leading research institution. This particular special issue, featuring five articles, examines both Turco-Italian perspectives on regional and global issues as well as bilateral relations between the two countries. This issue looks at the current state of Turkish-Italian relations, the changes in the nature of this relationship, and the potential areas of cooperation on regional and global issues, particularly security in the Middle East and North Africa.