This essay endeavours to justify a transcultural approach to international studies by showing that contemporary Western approaches to the theory of knowledge (epistemology) demand it. Both (sophisticated) falsificationism and pragmatic realism (or pragmatism) require that scientific truth-claims be redeemed discursively in the community of scientific experts. Owing to special features of social science, the claims to be redeemed include claims pertaining to meaning and intention. Because in international studies these claims rely on culturally sensitive interpretations, the discipline itself must assume a multicultural character in its institutions and practises, particularly in its practises of inquiry.